With obesity levels that have become epidemic, a diet that contains an extreme amount of fat may sound absurd. But recent studies show high-fat foods and low in carbohydrates can improve kidney function in diabetic patients.
Ketogenic diet is a diet which is high in fat and low in carbohydrates, has previously been successfully used to eliminate or reduce seizures in children with epilepsy due to drug-resistant.
This is because when the body lacks carbohydrates and sugar, the body will use fat reserves for energy form.
The followers of the ketogenic diet is recommended to eat foods that have a lot of high fat, such as: meat. Conversely, foods that are high in carbohydrates, such as: bread, flour, rice, wheat, cereals, should be limited.
In a laboratory research in mice, researchers at Mount Sinai Hospital in New York found that a diet high in fat and low in carbohydrates can prevent major complications of diabetes that is renal failure, quoted by Epharmapedia. This study involved two groups of mice that are genetically inclined to have type 1 or type 2 of diabetes.
The research team fed rats in the first group on a standard diet of carbohydrates and a second group with the ketogenic diet consisting of 87 percent fat, 5 percent carbohydrate and 8 percent protein. After eight weeks, renal failure did not occur in groups of mice on the ketogenic diet.
Doctors speculate that perhaps the ketogenic diet can have positive effects for people with diabetes by blocking the harmful effects of excess glucose and sugar, but this can cause serious problems in people with diabetes who do not have enough insulin.
As time goes, the glucose content that is too much in the blood can damage the retina of the eyes, nerves, blood vessels, and kidneys. Kidney damage due to diabetes, commonly known as diabetic nephropathy, which is the main cause of kidney failure. Once kidney failure occurs, it would require dialysis or kidney replacement through transplantation.
This study has significant implications for thousands of Americans who are diagnosed with kidney failure because of diabetes and its complications because of other possibilities. This study intended to show that dietary intervention is sufficient to prevent serious complications of diabetes.
However, although these research results is promising, but this diet is too extreme to be used in adult patients who had chronic diabetes. But, the results of the study can contribute to identifying drug targets and pharmacological interventions that can have subsequent effects resemble the effects of the ketogenic diet.