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Tuesday, August 23, 2011

Antiretroviral Drugs for Children with HIV

Tuesday, August 23, 2011
Discomfort often makes children disobedient taking medicine, include Antiretroviral drugs. Whereas Antiretroviral drugs (ARVs) for HIV must be taken regularly. To overcome this, the experts develop drugs with special flavors that kids love.

It is estimated that every day there are 1,000 children infected with Human Immunodeficiency Virus (HIV). This usually occurs when an infected woman gave birth, then her baby is also infected with HIV. In effect, an estimated 700 children die every day from AIDS.

AIDS (Acquired Immune Deficiency Syndrome) is the final stage of HIV infection, which causes severe damage to the immune system. This condition gradually destroys the immune system, which makes it harder for the body to fight infection.

A relatively low treatment is available, but care is not available in poor countries. Plus pharmaceutical companies consider not see much profit in developing new treatment or better treatment for children with AIDS.

Actually there is available drugs to prevent HIV transmission from mother to child, but many HIV-infected pregnant women who just do not get it. Many women who have no access to prenatal care, so never get treatment even though it may at that time they have been diagnosed. Even if they do care, very few offer HIV testing for pregnant women.

Access to antiretroviral (ARV) prophylaxis or for optimal therapy is really inadequate. Not to mention there are other barriers, such as a rare alternative to breastfeeding their babies. So that is still found a large number of children born with HIV in poor countries.

This can spend years to develop drugs that are suitable for children. HIV drugs currently has a flavor that is less suitable for children.

Ideally, a drug for children should have a sense that can be tolerated by children. Currently there is a drug with a separate liquid preparation of several antiretroviral drugs for children less than 3 years, but have a sense which, according to the child is very uncomfortable. The drugs should also remain stable at tropical temperatures and is available in modest doses. The drugs also should not contraindicated or compatible with other HIV drugs for children, which may also be consumed by children.

TB is a highly prevalent disease which is a concomitant infection in people with HIV, so it is necessary to find ways to ensure that the drugs found no contraindication to TB drugs

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